Contact Information:

Adress:

Faculty of Chemistry, University of Wrocław,

14 F. Joliot-Curie St. 50-383 Wrocław, POLAND

Phone:

(+48) (71) 375 72 51 (Office 401)

Fax:

(+48) (71) 375 72 51

E-mail:

Titles and degrees:

• M.Sc. 1968
• Ph.D. 1973
• D.Sc. 1977
• Full Professor 1989
• Vice-dean of the Faculty of Chemistry, University of Wrocław (1995-1999)
• Member of the Senate of University of Wrocław (1995-1999)
• Vice-head of the Commission Molecular Biology and Biotechnology of the Wrocław division of the Polish Academy of Sciences (1991-1998)

Position Held Abroad:

• Visiting Professor at the University of Florence (1986-1987)
• Visiting Professor at the University of Sassari (1988-2001)
• Visiting Professor at the University of Lille (1981, 1982, 1983, 1985, 1987)
• Visiting Professor at the University of Dunkerque (1994-1995)
• Visiting Professor at the University of Paris Nord (1994-2004)
• Visiting Professor at the University of Strasbourg (since 2002)
• Visiting Professor at the University of Siena (since 1999)
• Visiting Professor at the University of Ferrara (since 1999)
• Visiting Professor at the University of Florence (since 2000)

Professional Membership:

• Member of the Polish Chemical Society, Polish Biochemical Society, Polish Biophysical Society, Society of Biological Inorganic Chemistry (SBIC)
• Fellow of the Royal Society of Chemistry (CChem FRSC) (since 1999)
• Chartered Scientist of the Royal Society of Chemistry (Csci CChem FRSC) (since 2004)
• Member of the Scientific Council of the Center of Molecular and Macromolecular Researches of the Polish Academy of Science (PAN) (2003-2006)
• Member of the Scientific Council of the Laboratory of Structural Researches (UCZT) (since 2005)
• Member of the Alberta Prion Research Institute (Canada) (since 2005)
• Member of the Central Commission for Scientific Degrees and Titles (since 1997)
• Expert in Pilot Foresight Project in the "Health and Life" research area of the Ministry of Science and Information Society Technologies

Editorial Activity:

• Member of International Advisory Editorial Board of JCS Dalton Transaction (1997-2003)
• Member of International Advisory Editorial Board of New Journal of Chemistry (since 2003)
• Member of International Advisory Editorial Board of Polish Journal of Chemistry (since 2003)
• Member of Editorial Board of Inorganica Chimica Acta (1982-1989
• Member of Editorial Board of Metal Based Drugs (1992-1996)
• Member of Editorial Board of Bioinorganic Chemistry and Applications (since 2002)
• Member of Editorial Board of Journal of Inorganic Biochemistry (since 2006)

Scientific Activity:

• Chairman of the Managmenet Committee of COST Action D8 "Chemistry of Metals in Medicine" (since 2000)
• Coordinator of COST Action D8 "Molecular Mechanisms of Metal-Induced Toxicity and Carcinogenicity" (1998-2001)
• Polish delegate to the Management Committee for COST Action D20 "Metal Compounds in the Treatment of Cancer and Viral Diseases MCCV" (since 2001)
• Member of the working group in COST Action D21 "Metalloenzymes and Chemical Biomimetics" (since 2001)
• Polish delegate to the Management Committee for COST Action D34 "Molecular Targeting and Drug Design in Neurological and Bacterial Diseases"
• Member of the working group in COST Action D34/00605 "Development of Novel Targeted Chelators to Protect Against Oxidative Stress-Induced Neurodegenerative Diseases"

List of Publications since 2003:

• 1. M.Remelli, M.Łuczkowski, A.M.Bonna, Z.Mackiewicz, C.Conato, H.Kozłowski "Cu(II) ion coordination to SPARC: a model study on short fragments." New J.Chem. , 27 , 245-250 (2003)
• 2. E.Chruścińska, I.Derdowska, H.Kozłowski, B.Lammek, M.Łuczkowski, J.Świątek-Kozłowska "Unusual gain in the coordination ability of vasopressin-like peptides towards Cu ²⁺ ions by insertionof the highly hydrophobic side chain." New J.Chem. , 27 , 251-256 (2003)
• 3. M.Łuczkowski, H.Kozłowski, A.Łęgowska, K.Rolka, M.Remelli, "The possible role of Gly residues in prion octarepeat region in coordination of Cu ²⁺ ions." J.Chem.Soc., Dalton Trans. , 619-624 (2003)
• 4. N.D.Amelio, E.Gaggelli, A.Gajewska, H.Kochman, K.Kochman, H.Kozłowski, Z.Latajka, P.Młynarz, J.Panek, G.Valensin "Structural Analysis and Sheep Pituitary Receptor Binding of GnRH and Its Complexes with Metal Ions." J.Inorg.Biochem. , 94 , 28-35 (2003)
• 5. C.Conato, W.Kamysz, H.Kozłowski, M.Łuczkowski, Z.Maćkiewicz, F.Mancini, P.Młynarz, M.Remelli, D.Valensin, G.Valensin "Cu(II) Ion Coordination to an Unprotected Pentadecapeptide Containing Two His Residues: Competition between the Terminal Amino and the Side-Chain Imidazole Nitrogen Donors." Eur.J.Inorg.Chem. , 1694-1702 (2003)
• 6. A.Kaczor, J.Szczepański, M.Vala, H.Kozłowski, L.M.Proniewicz "Infrared Absorption Spectra of 2-(Hydroxyimino)propanohydroxamic and Oxalodihydroxamic Acids Isolated in Argon Matrices." Phys.Chem.Chem.Phys. 5 , 2337-2343 (2003)
• 7. M.Drąg, R.Latajka, E.Gumienna-Kontecka, H.Kozłowski, P.Kafarski "Stereoselective Synthesis, Solution Structure and Metal Complexes of (1S,2S)-2-Amino-1-hydroxyalkylphosphonic Acids." Tetrahedron: Asymmetry , 14 , 1837-1845 (2003)
• 8. M.Orfei, M.C.Alcaro, G.Marcon, M.Chelli, M.Ginanneschi, H.Kozłowski, J.Brasuń, L.Messori "Modeling of Copper(II) Sites in Proteins Based on Histidyl and Glycyl Residues." J.Inorg.Biochem. , 97 , 299-307 (2003)
• 9. H.Tayeb-Bel Haj, M.Salerno, W.Priebe, H.Kozłowski, A.Garnier-Suillerot "New Findings in the Study on the Interaction of Bisdaunorubicin and Its Monomeric Analogues with Naked and Nucleus DNA." Chemico-Biological Interactions , 145 , 349-358 (2003)
• 10. S.Sobek, B.Boduszek, H.Kozłowski "Aminomethylphosphonate ligands containing imidazole side chain are powerful ligands for Cu(II) and Ni(II) ions." Inorg.Chim.Acta , 355C , 462-465 (2003)
• 11. C.Conato, H.Kozłowski, J.Świątek-Kozłowska, P.Młynarz, M.Remelli, S.Silvestri "Formation equilibria of nickel complexes with glycyl-histidyl-lysine and two synthetic analogues." J.Inorg.Biochem. , 98 , 153-160(2004)
• 12. D.Valensin, F.M.Mancini, M.Łuczkowski, A.Janicka, K.Wiśniewska, E.Gaggelli, G.Valensin, L.Łankiewicz, H.Kozłowski "Identification of a Novel High Affinity Copper Binding Site in the APP (145-155) Fragment of Amyloid Precursor Protein." Dalton Trans. , 16-22 (2004)
• 13. F.Meyer, H.Kozłowski "Nickel." In Comprehensive Coord. Chem. II , J.A.McCleverly and T.J.Meyer Eds., Elsevier, Amsterdam, 2004, Vol.6 , pp. 247-554.
• 14. K.Małek, M.Vala, H.Kozłowski, L.M. Proniewicz "Experimental and Theoretical NMR Study of Oxocarboxylic Acid Oximes." Magn.Reson.Chem. , 42 , 23-29 (2004)
• 15. B.Belosi, E.Gaggelli, R.Guerrini, H.Kozłowski, M.Łuczkowski, F.M.Mancini, M.Remelli, D.Valensin, G. Valensin "Copper Binding to the Neurotoxic Peptide PrP106-126. Thermodynamic and Structural Studies." ChemBioChem. , 5 , 349-359 (2004)
• 16. E.Gumienna-Kontecka, J.Gałęzowska, M.Drąg, R.Latajka, P.Kafarski, H.Kozłowski "Coordination abilitites of substituted ß-aminophosphonates towards Cu ²⁺ and Zn ²⁺ ions." Inorg.Chim.Acta , 357 , 1632-1636 (2004)
• 17. D.Valensin, M.Łuczkowski, F.M.Mancini, A.Łęgowska, E.Gaggelli, G.Valensin, K.Rolka, H.Kozłowski "The Dimeric and Tetrameric Octarepeat Fragments of Prion Protein Behave Differently to Its Monomeric Unit." Dalton Trans. , 1284-1293 (2004)
• 18. M.L.Ganadu, M.Aru, G.M.Mura, A.Coi, P.Młynarz, H.Kozłowski "Effects of Divalent Metal Ions on the B-Crystallin chaperone-like Activity. Spectroscopic Evidence for a Complex between Copper(II) and Protein." J.Inorg.Biochem. , 98 , 1103-1109 (2004)
• 19. M.A.Zoroddu, M.Peana, T.Kowalik-Jankowska, H.Kozłowski, M.Costa "Nickel(II) Binding to Cap43 Protein Fragments." J.Inorg.Biochem. , 98 , 931-939 (2004)
• 20. M.Barańska, W.Łasocha, H.Kozłowski, L.M.Proniewicz "New solid state Ni(II)-famotidine square-planar complex; powder diffraction and spectroscopic studies." J.Inorg.Biochem. , 98 , 995-1001 (2004)
• 21. D.R.Brown, H.Kozłowski "Biological Inorganic and Bioinorganic Chemistry of Neurodegeneration Based on Prion and Alzheimer Diseases." Dalton Trans. , 1907-1917 (2004)
• 22. P.Stańczak, M.Łuczkowski, P.Juszczyk, Z.Grzonka, H.Kozłowski "Interactions of Cu ²⁺ Ions with Chicken Prion tandem Repeats." Dalton Trans. , 2102-2107 (2004)
• 23. H.Kozłowski "Bioligands as effective chelating agents for Ni(II) ions (in russ)." Rossijskij Chimiczeskij Żurnał , 48 , 24-29 (2004)
• 24. H.Kozłowski "Chemia i medycyna." In Misja Chemii , B.Marciniec Ed., Wydawnictwo Poznańskie, Poznań, 2004, p.97-112.
• 25. T.Karavelas, M.Mylonas, G.Malandrinos, J.C.Plakatouras, N.Hadjiliadis, P.Młynarz, H.Kozłowski, "Coordination properties of Cu(II) and Ni(II) ions towards the C-terminal peptide fragment - ELAKHA - of histone H2A." J.Inorg.Biochem. , 99 , 606-615 (2005)
• 26. E.Gaggelli, F.Bernardi, E.Molteni, R.Pogni, D.Valensin, G. Valensin, M.Remelli, M.Łuczkowski, H.Kozłowski "Interaction of the Human Prion PrP(106-126) Sequence with Copper(II), Manganese(II) and Zinc(II): NMR and EPR Studies." J.Am.Chem.Soc. , 127 , 996-1006 (2005)
• 27. J.Gałęzowska, S.Sobek, M.Drąg, A.Mucha, P.Kafarski, H.Kozłowski "Specific Interactions of Divalent Metal Ions with Phosphonic Analogues of Dipeptide Inhibitors of Proteases.", Polish J.Chem. , 79 , 603-617 (2005)
• 28. O.M.Kanderal, H.Kozłowski, A.Dobosz, J.Świątek-Kozłowska, F.Meyer, I.O.Fritsky "Effect of metal ionic radius and chelate rings alternation motif on stabilization of trivalent nickel and copper in binuclear complexes with double cis-oximato bridges." Dalton Trans. , 1428-1437 (2005)
• 29. E.Gaggelli, H.Kozłowski, D.Valensin, G.Valensin "NMR Studies on Cu(II)-Peptide Complexes: Exchange Kinetics and Determination of Structures in Solution." Mol.BioSyst. , 1 , 79-84 (2005)
• 30. K.Małek, H.Kozłowski, L.M. Proniewicz "Interaction of Na(I), Ni(II) and Cu(II) with 2-Cyano-2-(hydroxyimino)acetic Acid. Spectroscopic and Theoretical Studies." Polyhedron , 24 , 1175-1184 (2005)
• 31. P.Stańczak, D.Valensin, P.Juszczyk, Z.Grzonka, G.Valensin, F.Bernardi, E.Molteni, E.Gaggelli, H.Kozłowski "Fine tuning the structure of the Cu ²⁺ complex with the prion protein chicken repeat by proline isomerization." Chem.Commun. , 3298-3300 (2005)
• 32. K.Nakamura, M.Kodaka, I.M.El-Mehasseb, A.Gajewska, H.Okuno, E.Ochwanowska, B.Witek, H.Kozłowski, K.Kochman "Further Structural analysis of GnRH complexes with metal ions." Neuroendocrinology Letters , 26 , 247-252 (2005)
• 33. M.Remelli, M.Donatoni, R.Guerrini, A.Janicka, P.Pretegiani, H.Kozłowski "Copper-ion interaction with the 106-113 domain of the prion protein: a solution-equilibria study on model peptides." Dalton Trans. , 2876-2885 (2005)
• 34. P.Stańczak, D.Valensin, P.Juszczyk, Z.Grzonka, C.Migliorini, E.Molteni, G.Valensin, E.Gaggelli, H.Kozłowski "The structure and stability of the Cu ²⁺ complexes with tandem repeat of the chicken prion." Biochemistry , 44 , 12940-12954 (2005)
• 35. J.Gałęzowska, E.Gumienna-Kontecka, E.Matczak-Jon, S.Sobek, V.Videnova-Adrabińska, H.Kozłowski "Specific interactions of metal ions with ligands containing phosphonic function." Polish Journal of Environmental Studies , 14, Supl.II , 56-63 (2005)
• 36. H.Kozłowski, T.Kowalik-Jankowska, M.Jeżowska-Bojczuk "Chemical and Biological Aspects of Cu ²⁺ Interactions with Peptides and Aminoglycosides." Coord.Chem.Rev. , 249 , 2323-2334 (2005)
• 37. T.K.Olszewski, B.Boduszek, S.Sobek, H.Kozłowski "Synthesis of thiazole aminophosphine oxides, aminophosphonic and aminophosphinic acids and Cu(II) binding abilities of thiazole aminophosphonic acids." Tetrahedron , 62 , 2183-2189, (2006)
• 38. E.Podstawka, H.Kozłowski, L.M.Proniewicz "Molecular structure study of dimethoxyphenyl-substituted phosphonodipeptides by infrared, Raman and surface enhanced Raman spectroscopies." J.Raman Spectrosc. , 37 , 574-584 (2006)
• 39. F.D.Sokołov, N.G.Zabirov, L.N.Yamalieva, V.G.Shtyrlin, R.R.Garipov, V.V.Brusko, A.Yu.Verat, S.V.Baranov, P.Młynarz, T.Głowiak, H.Kozłowski "Coordination diversity of N-phosphoryl-N'-phenylthiourea (LH) towards Co(II), Ni(II) and Pd(II) cations. Crystal structure of ML ₂ -N,S and ML ₂ -O,S chelates." Inorg.Chim.Acta , 359 , 2087-2096 (2006)
• 40.H.Kozłowski, M.Łuczkowski, D.Valensin, G.Valensin "Metal ion binding properties of proteins related to neurodegeneration." in "Metal Ions in Life Sciences", Vol.1 A.Sigel, H.Sigel and R.K.O.Sigel Eds., Wiley & Sons. 1 , 61-87 (2006)
• 41. E.Gaggelli, H.Kozłowski, D.Valensin, G.Valensin "Copper homeostasis and neurodegenerative disorders (Alzheimer's, prion and Parkinson's diseases and amyotrophic lateral sclerosis)." Chem.Rev. 106 , 1995-2044 (2006)
• 42. D.U.Miodragović, G.A.Bogdanović, Z.M.Miodragović, M.D.Radulović, S.B.Novaković, G.N.Kaluderović, H.Kozłowski "Interesting coordination abilities of antiulcer drug famotidine and antimicrobial activity of drug and its cobalt(III) complex." J.Inorg.Biochem. , 100 , 1568-1574 (2006)
• 43. J.Gałęzowska, R.Janicki, A.Mondry, R.Burgada,T.Bailly, M.Lecouvey, H.Kozłowski "Co-ordination ability of trans-cyclohexane-1,2-diamine-N,N,N,N,-tetrakis- (methylenephosphonic acid) towards lanthanide(III) ions." Dalton Trans. 4384-4394 (2006)
• 44. P.Stańczak, D.Valensin, E.Porciatti, E.Jankowska, Z.Grzonka, E.Molteni, E.Gaggelli, G.Valensin, H.Kozłowski "Tandem Repeat-Like Domain of "Similar to Prion Protein" (StPrP) of Japanese Pufferfish Binds Cu(II) as Effectively as the Mammalian Protein" Biochemistry , 45 , 12227-12239 (2006)
• 45. I.O.Fritsky, H.Kozłowski, O.M.Kanderal, M.Haukka, J.Świątek-Kozłowska, E.Gumienna-Kontecka, F.Meyer "Efficient stabilization of copper(III) in tetraqaza pseudo-macrocyclic oxime-and-hydrazide ligands with adjustable cavity size." Chem.Commun. , 4125-4127 (2006)
• 46. H.Kozłowski, D.Brown, G.Valensin "Metallochemistry of Neurodegeneration: Biological, Chemical and Genetic Aspects." Ed. RSC Publishing, p.1-281 Cambridge, (2006)
• 47. A. Janicka, P. Stańczak and H. Kozłowski "Impact of copper ions on chemistry and biology of prion protein." Pol.J.Chem. , 81 , 1-13 (2007)
• 48. P.Stańczak, H.Kozłowski "Can chicken and human PrPs possess SOD-like activity after ß-cleavage?" Biochem Biophys Res Commun. , 352 , 198-202 (2007)
• 49. T.Kowalik-Jankowska, H.Kozłowski, E.Farkas, I.Sovago "Nickel ion complexes of amino acids and peptides." in "Metal Ions in Life Sciences", Vol.2, A.Sigel, H.Sigel and R.K.O.Sigel Eds., Wiley & Sons. 2 , 63-108 (2007)
• 50. F.Berti, E.Gaggelli, R.Guerrini, A.Janicka, H.Kozłowski, A.Łęgowska, H. Miecznikowska, C.Migliorini, R.Pogni, M.Remelli, K.Rolka, D.Valensin, G.Valensin "Structural and dynamic characterization of copper(II) binding of the human prion protein outside the octarepeat region." Chem.Eur.J., 13 , 1991-2001 (2007)
• 51. D.A.Safin, M.G.Babashkina, F.D.Sokołov, N.G.Zabirov, J.Gałęzowska, H.Kozłowski "Complexes of novel N-(diisopropxythiophosphoryl)thiourea derivative of 1,4,8,11-tetraazacyclotetradecane with Na⁺, K⁺ and Cu(PPh3)²⁺ cations." Polyhedron , 26 , 1113-1116 (2007)
• 52. A.Odani, H.Kozłowski, J.Świątek-Kozłowska, J.Brasuń, B.P.Operschall, H.Sigel "Extent of metal ion-sulfur binding in complexes of thiouracil nucleosides and nucleotides in aqueous solution." J.Inorg.Biochem. , 101 , 727-735 (2007)
• 53. D.A.Safin, P.Młynarz, E.Hahn, M.G.Babashkina, F.D.Sokołov, N.G.Zabirov, J.Gałęzowska, H.Kozłowski "Cobalt(II) complexes with N-thioacylamidophosphates and 2,2'-bipyridyl and 1,10-phenanthroline. Crystal structures, solution ¹H NMR spectral and magnetic properties." Z.Anorg.Allg.Chem. , 633 , 1472-1479 (2007)
• 54. T.K.Olszewski, J.Gałęzowska, B.Boduszek, H.Kozłowski "New heterocyclic mono- and bis(?-hydroxymethyl)-phosphinic acids: synthesis and Cu(II) binding abilities." Eur.J.Org.Chem. , 3539-3546 (2007)
• 55. M.Seredyuk, M.Haukka, I.Fritsky, H.Kozłowski, R.Krämer, V.A. Pavlenko, P.Gütlich "Bis(3,4-dimethyl-1H-pyrazolyl)selenide-a new bidentate bent connector for preparation of 1D and 2D co-ordination polymers." Dalton Trans. , 3183-3194 (2007)
• 56. F.D.Sokolov, S.V.Baranov, D.A.Safin, F.E. Hahn, M.Kubiak, T.Pape, M.G.Babashkina, N.G.Zabirov, J.Gałęzowska, H.Kozłowski, R.A.Cherkasov "The influence of the intramolecular hydrogen bond on the 1,3-N,S- and 1,5-O,S-coordination of N-phosphoryl-N’-(R)-thioureas with Ni(II) and Pd(II)." New J. Chem. , 31 1661-1667 (2007)
• 57. P.Stańczak, P.Juszczyk, Z.Grzonka, H.Kozłowski "The whole hexapeptide repeats domain from avian PrP displays untypical hallmarks in aspect of the Cu2+ complexes formation." FEBS Lett. , 581 , 4544-4548 (2007)
• 58. D.A.Safin, P.Młynarz, F.D.Sokolov, M.Kubiak, F.E.Hahn, M.G.Babashkina, N.G.Zabirov, J.Gałęzowska, H.Kozłowski "Rich magnetic chemistry of cobalt(II) complexes with N-phosphorylthioureas. Crystal structure and solution 1H NMR spectral properties." Z. Angor. Allg. Chem. , 633 , 2089-2096 (2007)
• 59. J.Gałęzowska, Ł.Szyrwiel, P.Młynarz, S.Śliwińska, P.Kafarski, H.Kozłowski "Coordination abilities of difunctional, diaminophosphonic acid and its dipeptides towards Cu(II) ions." Polyhedron , 26 , 4287-4293 (2007)
• 60. K.Kulon, D.Wozniak, K.Wegner, Z.Grzonka, H.Kozłowski "Specific interactions of metal ions with Cys-Xaa-Cys unit inserted into the peptide sequence." J. Inorg.Biochem. , 101 , 1699-1706 (2007)
• 61. F.D.Sokolow, M.G.Babashkina, D.A.Safin, A.I.Rakhmatullin, F.Fayon, N.G.Zabirov, M.Bolte, V.V.Brusko, J.Gałęzowska, H.Kozłowski "Complexes of N- phosphorylthioureas (HL) with copper(I). Crystal structures of [Cu3L3] and [Cu(PPH3)2L] chelates." Dalton Trans. , 4693-4700 (2007)
• 62. E.Gaggelli, A.Janicka-Kłos, E.Jankowska, H.Kozłowski, C.Migliorini, E.Molteni, D.Valensin, G.Valensin, E.Wieczerzak "NMR Studies of the Zn2+ Interactions with Rat and Human Andy-Amyloid (1-28) Peptides in Water Micelle Environment." J. Phys. Chem. B , 112 , 100-109 (2008)
• 63. E.Gaggelli, Z.Grzonka, H.Kozłowski, C.Migliorini, E.Molteni, D.Valensin, G.Valensin " Cu2+ complex with the rat AB(1-28) fragment." Chem. Commun. , 341-343 (2008)
• 64. Y.S.Moroz, T.Yu.Sliva, K.Kulon, H.Kozłowski, I.O.Fritsky "Dichlorido{2-hydroxyimino-N’-[1-(2-pyridyl)ethyl-idene]propanohydrazide-?3N,N’O}Zinc(II) Hemihydrate." Acta Crystallogr. E , E64 , m353-m354 (2008)
• 65. T.Karavelas, G.Malandrinos, N.Hadjiliadis, P.Młynarz, H.Kozłowski, M.Barsam, I.Butler "Coordination properties of Cu(II) and Ni(II) ions towards the C-terminal peptide fragment - TYTEHA- of histone H4." Dalton Trans. , 1215-1223 (2008)
• 66. Banci L., Bertini I., Ciofi-Baffoni S., Janicka A., Martinelli M., Kozłowski H., Palumaa P. "A structural-dynamical characterization of human Cox17." J. Biol. Chem. , 283 ,7912-7920 (2008)
• 67. Brasuń J, Matera A., Sochacka E., Swiatek-Kozłowska J., Kozłowski H., Operschall B. P., Sigel H. "Acid-base and metal ion binding properties of 2-thiocytidine in aqueous solution." J. Biol. Inorg.Chem. , 13 ,663-674 (2008)
• 68. Crisponi G, Nurchi V. M., Pivetta T., Gałęzowska J., Gumienna-Kontecka E., Bailly T., Burgada R., Kozłowski H. "Towards a new attenuating compound: a potentiometric, spectrophotometric and NMR equilibrium study on Fe(III), Al.(III) and a new tetradentate mixed bisphosphonate-hydroxypyridinonate ligand." J. Inorg. Biochem. , 102 1486-1494 (2008)
• 69. Gaggelli E., Grzonka Z., Kozłowski H., Migliorini C., Molteni E., Valensin D., Valensin G. " Structural features of the Cu(II) complex with the rat A beta(1-28) fragment." Chem. Commun. , 341-343 (2008)
• 70. Gaggelli E., Janicka-Kłos A., Jankowska E., Kozłowski H., Migliorini C., Molteni E., Valensin D., Valensin G., Wieczerzak E. " NMR studies of the Zn2+ interactions with rat and human?-amyloid (1-28) peptides in water-micelle environment." J. Phys. Chem. B. , 112 , 100-109 (2008)
• 71. Gaggelli E., Jankowska E., Kozłowski H., Marcinkowska A., Migliorini C., Stańczak P., Valensin D., Valensin G. " Structural characterization of the intra- and inter-repeat copper binding modes within the N-terminal region of "prion related protein" (PrP-rel-2) of zebrafish." J. Phys. Chem. B. , 112 , 15140-15150 (2008)
• 72. Gralka E. K., Valensin D., Porciatti E., Gajda C., Gaggelli E., Valensin G., Kamysz W., Nadolny R., Guerrini R., Bacco D., Remelli M., Kozłowski H. " CuII binding sites located at His-96 and His-111 of the human prion protein: thermodynamic and spectroscopic studies on model peptides." Dalton Trans. , 5207-5219 (2008)
• 73. Janicka-Kłos A., Juszczyk P., Grzonka Z., Kozłowski H. "Competition between the albumin and three histidine fragment of amyloid precursor protein sites to bind Cu(II)." Polyhedron. , 27 , 1511-1516 (2008)
• 74. Karavelas T., Malandrinos G., Hadjiliadis N., Młynarz P., Kozłowski H., Barsam M., Butler I. "Coordination properties of Cu(II) and Ni(II) ions towards the C-terminal peptide fragment-TYTEHA- of histone H4." Dalton Trans. , 1215-1223 (2008)
• 75. Kowalik-Jankowska T., Biega Ł., Kuczer M., Konopińska D. "Copper(II) complexes of Neobelliera Bullata Trypsin Modulating Oostatic Factor and its analogues." J. Inorg. Biochem. , 102 , 1615-1622 (2008)
• 76. Kowalik-Jankowska T., Rajewska A., Jankowska E., Grzonka Z. "Products of Cu(II)-catalyzed oxidation of alfa-synuclein fragments containing M1-D2 and H50 residues in the presence of hydrogen peroxide." Dalton Trans. , 832-838 (2008)
• 77. Kozłowski H., Janicka-Kłos A., Stańczak P., Valensin D., Valensin G., Kulon K. "Specificity in the Cu2+ interactions with prion protein fragments and related His-rich peptides from mammals to fishes." Coord. Chem. Rev. , 252 1069-1078 (2008)
• 78. Kucharczyk M., Brzezowska M., Macišg A, Lis T., Jeżowska-Bojczuk M. "Structural features of the Cu2+-vancomycin complex." J. Inorg. Biochem. , 102 , 936-942 (2008)
• 79. Kulon K., Valensin D., Kamysz W., Nadolny R., Gaggelli E., Valensin G., Kozłowski H. "Binding of Ni2+ and Cu2+ ions peptides with a Cys-His motif." Dalton Trans. , 5323-5330 (2008)
• 80. Kulon K., Valensin D., Kamysz W., Valensin G., Nadolski P., Porciatti E., Gaggelli E., Kozłowski H. "The His-His sequence of the antimicrobial peptide demegen P-113 makes it very attractive ligand for Cu2+." J. Inorg. Biochem. , 102 , 960-972 (2008)
• 81. Moroz Y. S., Kulon K., Haukka M., Gumienna-Kontecka E., Kozłowski H., Meyer F., Fritsky I. O. "Synthesis and structure of [2 x 2] molecular grid copper(II) and nickel(II) complexes with a new polydentate oxime-containing Schiff base ligand." Inorg. Chem. , 47 , 5656-5665 (2008)
• 82. Moroz Y. S., Sliva T. Yu., Kulon K., Kozłowski H., Fritsky I. O. "Dichloro{2-hydroxyimino-N'-[1-(2--pyridyl)ethyl-idene]propanohydrazide-k3N,N',O}zinc(II) hemihydrate." Acta Cryst. Sect. E , E64 , m353-m354, 1-8 (2008)
• 83. Mucha A., Bal W., Jeżowska-Bojczuk M. "Comparative studies of coordination properties of puromycin and puromycin aminonucleoside towards copper(II) ions." J. Inorg. Biochem. , 46-52 (2008)
• 84. Mucha A., Knobloch B., Jeżowska-Bojczuk M., Kozłowski H., Sigel R. K. O. "Comparison of the acid-base properties of ribose and 2'-deoxyribose nucleotides." Chem. Eur. J. , 14 , 6663-6671 (2008)
• 85. Mucha A., Knobloch B., Jeżowska-Bojczuk M., Kozłowski H., Sigel R. K. O. "Effect of the riboseversus2'-deoxyribose residue on the metal ion-binding properties of purine nucleotides." Dalton Trans. , 5368-5377 (2008)
• 86. Podsiadły H. "Interaction of vanadium(III) with imidazole carboxylic acids." Polyhedron. , 27 , 1563-1572 (2008)
• 87. Podsiadły H. "Speciation in the vanadium(III)-carnosine system." J. Solution Chem. , 37 , 1207-1215 (2008)
• 88. Ribeiro da Silva M. A. V., Santos L. M. N. B. F., Giera E. "Standard molar enthalpies of formation of zinc(II) beta-diketonates and monothio-beta-diketonates." J. Chem. Thermodyn. , 40 , 1318-1324 (2008)
• 89. Safin D. A., Sokolov F. D., Baranov S. V., Szyrwiel Ł., Babashkina M. G., Shakirova E. R., Hahn F. E., Kozłowski H. "Coordination mode of the nickel(II) cation withN-diisopropoxyphosphinyl-pbromothiobenzamide." Z. Anorg. Allg. Chem. , 634 , 835-838 (2008)
• 90. Safin D. A., Sokolov F. D., Szyrwiel Ł., Babashkina M. G., Gimadiev T. R., Hahn F. E., Kozłowski H., Krivolapov D. B., Litvinov I. A. "Nickel(II) complexes with N-(thio)phosphorylthioureas AdNHC(S)NHP(X)(OiPr)2: versatile coordination of phosphoryl ( X= O) and thiophosphoryl (X = S) derivatives." Polyhedron. , 27 , 2271-2276 (2008)
• 91. Safin D. A., Sokolov F. D., Szyrwiel Ł., Baranov S. V., Babashkina M. G., Gimadiev T. R., Kozłowski H. "MonodentateS-vs. bidentate 1,5-O,S-coordination ofN-phosphoryl-N'-(R)-thioureas with Pd(II)." Polyhedron. , 27 , 1995-1998 (2008)
• 92. Safin D. A., Szyrwiel Ł., Baranov S. V., Sokolov F. D., Babashkina M. G., Kozłowski H. "Intramolecular hydrogen bond controlled monodentate S-coordination of N-phosphoryl-N'- (R)-thioureas with Pd(II)." Inorg. Chem. Commun. , 11 , 330-333 (2008)
• 93. Szczepanik W., Krężel A., Brzezowska M., Dworniczek E., Jeżowska-Bojczuk M. "Impact of Cu(II) ions on the structure and antimicrobial properties of sisomicin, an aminoglycoside antibiotic." Inorg. Chim. Acta. , 361 , 2659-2666 (2008)
• 94. Szyrwiel Ł., Jankowska E., Janicka-Kłos A., Szewczuk Z., Valensin D., Kozłowski H. "Zn(II) ions bind very efficiently to tandem repeat region of "prion related protein" (PrP-rel-2) of zebra-fish. MS and potentiometric evidence." Dalton Trans. , 6117-6120 (2008)
• 95. Zoroddu M. A., Kowalik-Jankowska T., Medici S., Peana M., Kozłowski H. "Copper(II) binding to Cap43 protein fragments." Dalton Trans. , 6127-6134 (2008)
• 96. Magdalena Zyrek, Elzbieta Gumienna-Kontecka, Zbigniew Szewczuk, Igor O. Fritsky, and Henryk Kozlowski "Copper(II)-aminohydroxamate ternary complexes evidenced by mass spektrometry." Arkivoc. , 145-157 (2009)
• 97. Joanna Galezowska, Pawel Kafarski, Henryk Kozlowski, Piotr Mlynarz, Valeria M. Nurchi, Tiziana Pivetta " N, Nâ??-Ethylenediaminobis(benzylphosphonic acid) as a potent class of chelators for metal ions." Inorg. Chim. Acta , 362 , 707-713 (2009)
• 98. A. Michaluk, A. Gajewska, K. Kulon, H. Kozlowski, K. Kochman, J.. Kowalczyk, M. Czauderna "Direct liquid chromatography with photodiode and fluorescence detection for simultaneous Quantification of gonadoliberin-releasing hormone its complexes with Cu(II) and catabolites." Pol. J. Chem. , 83 , 383-390 (2009)
• 99. Maria G. Babashkina, Damir A. Safin, Lukasz Szyrwiel, Maria Kubiak, Felix D. Sokolov, Yuri V.Starikov, and Henryk Kozlowski "Complexes of N-Thiophosphorylthiourea -NaphthylNHC(S)NHP(S)(OiPr)2 (HL) with Copper(I). Crystal Structures of HL and Cu(PPh3)2L." Z. Anorg. Allg. Chem. , 635 , 554-557 (2009)
• 100.Gianni Valensin, Elena Molteni, Daniela Valensin, Magdalena Taraszkiewicz, Henryk Kozlowski "Molecular dynamics study of the Cu2+ binding-induced â??structuring of the N-terminal domain of Human prion protein." J.Phys. Chem. B , 113 , 3277-3279 (2009)
• 101.E. Gralka, D. Valensin, K. Gajda, D. Bacco, L. Szyrwiel, M. Remelli, G. Valensin, W. Kamysz, W. Baranska-Rybak and H. Kozlowski "Copper(II) coordination outside the tandem repeat region of an unstructured domain of chicken prion protein." Mol. BioSystems , 5 , 497 - 510 (2009)
• 102.D.A.Safin, A.Klein,M.G.Babashkina, H.Noth,D.B.Krivoolapov, I.A.Litvinov, H. Kozlowski "Versatile coordination of N-(diisopropoxyphosphoryl)-p-bromothiobenzamide towards Zn(II) and Cd(II)." Polyhedron , 28 , 1504-1510 (2009)
• 103. F.Camponeschi, E.Gaggelli, H.Kozłowski,D.Valensin, G.Valensin "Structural features of the Zn2+ complex with the single repeat region of 'Prion RelatedProtein' (PrP-rel-2) of Zebrafish zPrP (63-70) fragment." Dalton Trans. , 24 , 4643-4645 (2009)
• 104.L.V.Penkova, A. Macišg, E.V.Rybak-Akimova,M.Haukka, V.A.Pavlenko, T.S.Iskenderov, H.Kozlowski,F.Mayer,I.O.Fristky "Efficient Catalytic Phosphate Ester Cleavage by Binuclear Zinc(II) Pyrazolate Complexes as Functional Models of Metallophosphatases." Inorg.Chem. , 48 , 6960-6971 (2009)
• 105.D. Valensin, Ł. Szyrwiel, F. Camponeschi, M. Rowinska-Zyrek, E. Molteni, E. Jankowska, A. Szymanska, E. Gaggelli, G. Valensin and H. Kozłowski "Heteronuclear and Homonuclear Cu2+ and Zn2+ Complexes with Multihistidine Peptides Based on Zebrafish Prion-like Protein." Inorg. Chem. , 48(15) , 7330 - 7340 (2009)
• 106.A.Sornosa Ten, N.Humbert, B.Verdejo, J.M.Linares, M.Elhabiri, J.Jezierska, C.Sorino,H.Kozlowski, A-M.Albrecht-Gary, E.Espana "Cu2+ coordination properties of a 2-pyridine Heptaamine Tripod: Characterization and Binding Mechanism." Inorg. Chem. , 48(18) , 8985 - 8997 (2009)
• 107. H. Kozlowski, A.Janicka-Klos, J.Brasuń,E. Gaggelli, D.Valensin, G.Valensin "Copper, iron and zink ions homeostasis and their role in neurodegenerative disorders." Coord. Chem. Rev. , 253 , 2665-2685 (2009)
• 108. M. Rowinska-Zyrek, D. Valensin, L. Szyrwiel, Z. Grzonka and H. Kozlowski "Specific interactions of Bi(III) with the Cys-Xaa-Cys unit of a peptide sequence." Dalton Trans. , 42 , 9131-9140 (2009)
• 109.M. Remelli, D. Valensin, D. Bacco, E. Gralka, R. Guerrini, C. Migliorini and H. Kozlowski "The complex-formation behaviour of His residues in the fifth Cu2+ binding site of human prion protein: a close look." New J. Chem. , 33 , 2300 - 2310 (2009)
• 110. D. Valensin, K. Gajda, E. Gralka, G. Valensin,W. Kamysz , H.Kozlowski "Copper binding to chicken and human prion protein amylodogenic regions:Differences and similarities revealed by Ni2+ as a diamagnetic probe." J.Inorg. Chem. , 104 , 71 -78 (2010)

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