bioinorganic and biomedical chemistry group
Research Topics:
- Structure and thermodynamics of bioinorganic systems
- Metal interactions with natural peptides and their derivatives, pesticides, nucleotides and nucleic acids
- Molecular mechanisms of metal-related toxicity and carcinogenesis
- Interactions of metal ions with different components of cell nucleus
- Interactions of metal ions with anticancer drugs
- Interactions of metal ions with aminosugars, sugar acids and aminoglycosidic antibiotics as potential mechanisms of increasing their bioactivity
- Modification of hormone bioactivity by various metal ions
- Structure and activity of metalloenzymes
- Chelating agents for toxic metals and effect of toxic metal on biomolecules
- Coordination ability of phosphorus analogs of amino acids and peptides
- Structure and function of enzymes
- Enzymes inhibition
- Impact of metal ions on biochemistry and chemistry of drugs
- Interaction and transport of drugs by serum proteins
- Mechanisms of electroreduction of metal complexes at mercury electrode
- Thermochemistry of coordination compounds
- Metal ions in neurodegeneration
- Impact of the disease on the level of various metals in the blood serum
